Much ado about nothing: Multiple imputation to balance unbalanced designs for two-way analysis of variance

Much ado about nothing?

I t all started with the submission of an unsolicited review on idiopathic pulmonary haemosiderosis by IOACHIMESCU et al. [1]. During the review process of this excellent manuscript, the idea evolved to launch a whole series on rare (orphan) interstitial lung disorders in the European Respiratory Journal. Why bother? Well, admittedly, these diseases are rare, but for the affected patient that d...

Much ado about nothing?

Much ado about nothing.

Much ado about nothing.

Much Ado about Nothing

Let us start with non-existent objects. I will assume a certain view of these. I will not defend it here; this has been done elsewhere.2 The point in what follows will be to apply it. So let me simply summarise the core points. Some objects do not exist: fictional characters, such as Sherlock Holmes; failed objects of scientific postulation, such as the mooted planet Vulcan; God (any one that y...